Eosinophilic Asthma Resource Centre
Educational platform focused on providing education in the pulmonology community and beyond
The Uncontrolled Asthma Resource Centre is an educational portal that helps healthcare professionals, pulmonologists, immunologists and allergologists optimize the management of patients with uncontrolled asthma and active eosinophilic inflammation.
Providing the latest research, along with fully available peer-reviewed articles, congress highlights videos, round table discussions, patient case studies and webcasts with key opinion leaders, the Resource Centre aims to disseminate knowledge of eosoinophilic airways disease. This freely available resource is hosted by Respiratory Medicine.
On the way to a consensus on eosinophilic asthma
Guest commentary by Dr. Stephanie Korn
Asthma is a heterogeneous disease, with recognizable clusters of clinical, functional and laboratory characteristics called ‘phenotypes’. Allergic asthma is the most easily recognized phenotype. Among the non-allergic phenotypes eosinophilic asthma (or asthma with eosinophilia), driven by an abnormal production of type 2 cytokines (e.g. interleukin-5 (IL-5) and IL-13) triggered by as yet unknown danger signals, still awaits precise characterization, even more so given the high clinical impact in particular of severe eosinophilic asthma (SEA) and the availability of effective treatment options …
Simultaneously increased fraction of exhaled nitric oxide levels and blood eosinophil counts relate to increased asthma morbidity
Malinovschi A, Janson C, Borres M, Alving KJ Allergy Clin Immunol. 2016; Volume 138, Issue 5, November 2016, Pages 1301-1308.e2
Exacerbation risk in severe asthma is stratified by inflammatory phenotype using longitudinal measures of sputum eosinophils
Walsh CJ, Zaihra T, Benedetti A, Fugère C, Olivenstein R, Lemière C, Hamid Q, Martin JGClin Exp Allergy. 2016 Oct;46(10):1291-302. doi: 10.1111/cea.12762. Epub 2016 Jun 27.
Guest commentary by Dr. Stephanie KornAsthma is a heterogeneous disease, with recognizable clusters of clinical, functional and laboratory characteristics called ‘phenotypes’. Allergic asthma is the...
Shabtai Varsano, David Segev, David Shitrit
Respiratory Medicine, Volume 123, February 2017, Pages 131-139
Denlinger LC, Phillips BR, Ramratnam S, Ross K, Bhakta NR, et al.; National Heart Lung and Blood Institute’s Severe Asthma Research Program-3 Investigators.Am J Respir Crit Care Med. 2017 Feb 1;195(3):302-313.
This online resource center has been supported through an unrestricted grant by TEVA Pharmaceuticals.