Eosinophilic Asthma Resource Centre

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Eosinophilic Asthma Resource Centre

Educational platform focused on providing education in the pulmonology community and beyond


Efficacy and safety of dupilumab as add-on therapy

Commentary by Dr. William W. Busse

Sally Wenzel and colleagues presented the findings of a large phase 2b study that evaluated the effects of dupilumab, an IL-4/IL-13 receptor antagonist, in patients with severe asthma. Earlier studies with dupilumab had shown that the administration of this monoclonal antibody allowed for the successful reduction of concomitant use of inhaled corticosteroids and long-acting beta-agonists without loss of asthma control and suggested that this particular monoclonal antibody may provide additional benefit for severe asthma patients with uncontrolled asthma despite optimal therapy with …


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Editorial Board

Jean Bousquet is Professor Emeritus at the University of Montpellier, France. A former President of the Société Française d’Allergologie et d’Immunologie Clinique, for 13 years Professor Bousquet was Director of the INSERM Laboratory for the Immunopathology of Asthma.

Roland Buhl is Professor of Medicine and Head of the Pulmonary Department at Mainz University Hospital. He qualified and received his doctorate from the University of Heidelberg and later trained in pulmonary medicine and allergology, first in Berlin and Frankfurt, and then at National Institutes of Health in the U.S., before receiving his Ph.D. from the University of Frankfurt.

William W. Busse M.D. has been on the faculty at the University of Wisconsin Medical School since 1974. Dr. Busse has served as head of the Allergy and Clinical Immunology Section and George R. and Elaine Love Professor and Chair of Medicine, and is a diplomat of the American Board of Internal Medicine and American Board of Allergy and Clinical Immunology.

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This online resource center has been supported through an unrestricted grant by TEVA Pharmaceuticals.